Featured Product
Upadacitinib key intermediates and API
Oral selective JAK1 — take intermediates, API, or both. Scale from R&D quantities to commercial supply, with impurity control and project-ready files.
- JAK1
- Once-daily oral
- Key intermediates
- API
Key intermediates
Building blocks from R&D quantities through commercial scale.
- R&D through commercial quantities
- Scoped to the grade and volume you name
Active pharmaceutical ingredient
API development supported by consistent quality and impurity control.
- Robust manufacturing and analytical controls
- Specs, COAs, methods and impurity data by project
Originator program — not a Unibest branded product
JAK0
Oral selective inhibitor (originator brand: Rinvoq)
Industry context
Upadacitinib is an oral, selective JAK1 inhibitor with proven value across immune-mediated inflammatory disease — rheumatoid arthritis, atopic dermatitis, ulcerative colitis and Crohn’s disease. Once-daily extended-release tablets are more convenient than injectable biologics. Multiple indications and long-term treatment demand make it a promising generic pipeline target — which is why key intermediates and API need a commercial-ready supply, not a research-only catalogue.
For manufacturers and marketers
01Marketing-authorisation holders
02Regional manufacturers
03Distributors
Not a consumer offer, and not originator-branded product.
Why this supply
Reliable scale, consistent impurity control, and files that match the project.
Reliable, scalable supply
Key intermediates are available from R&D quantities through commercial scale.
Consistent quality and impurity control
Robust manufacturing and analytical controls support reliable API development.
Flexible technical support
Specifications, COAs, analytical methods and impurity information are available according to project needs.
How a program starts
Same sequence whether you take intermediates, API, or both.
- 01
Scope
Grade, volume and whether you need intermediates, API, or both. We confirm what we can stand behind before work starts.
- 02
Align the file
Specification, CoA format and impurity expectations — written down while gaps are still cheap to close.
- 03
Qualify supply
Lots and/or commercial API against that spec. Audit findings stay in the same program plan.
- 04
Deliver and hold
First shipment, then change control from one owner.
Frequently asked
Ready to scope a supply?
Send the grade and a volume range. We reply with what we can stand behind.